Since our manuscript has been accepted to Neuron for publication in February, we’ve been invited to submit a possible design for the journal cover. Based on our story, I’ve designed several covers to show the role of the protein TROY in blocking axon regeneration. My first design is just a merge of two images showing the expression of TROY, but not another protein in mouse retina. There’s a shadow of a neuron superimposed on it to suggest that the TROY protein can prevent regeneration. The second is a photomosaic of many expression images, the composite of which shows a wooden horse, reminiscent of Odysseus’ device against the ill-fated city of the same name. The third combines the two ideas. Anyway, I’m probably gonna submit all three, but I’d really appreciate any suggestions you have to make them better!
The last image, I don't like the shape of the horse that's superimposed on the neurons. Is it just me – it doesn't look like the horse on the second image. Regarding the second image: the photomosaic of expression images is a cool idea – and it makes the TROY headline memorable. The edges look blurry though, and blends in with the background – is it the resolution of the image or what? The first image is nice also, but it's not as memorable as the other two. So, I would personally pick the second one. I think I would make a more informed decision after I saw more closeups of all the images.